螯合剂

Chelating Agents 螯合剂


The most common Chelating Agents are:最常见的螯合剂是：

    Edetate disodium (disodium EDTA, edathamil disodium, sodium edetate): IV infusion for emergency treatment of acute hypercalcemia in selected patients. edetate二钠（钠盐的EDTA ， edathamil钠盐，钠edetate ） ：静脉注射，紧急治疗急性高血钙症在选定的病人。

    Edetate calcium disodium (calcium disodium Versenate®, calcium EDTA, sodium calcium EDTA, edathamil calcium disodium, CaNa2-EDTA): can be used in conjunction with BAL in lead toxicity. edetate钙钠盐（钙钠盐versenate ® ，钙的EDTA ，钠，钙的EDTA ， edathamil钙钠盐， cana2 - EDTA ）的：可以用在与平衡中铅毒。 IV infusion preferred, but may be used IM.四，输液的首选，但可能会使用IM 。

    DMSA (dimercaptosuccinic acid, Succimer, Chemet®): an analogue of Dimercaprol that can be given orally for lead poisoning. dmsa （ dimercaptosuccinic酸， succimer ， chemet ® ） ：一个模拟的dimercaprol可以给予口头为铅中毒。
    D-penicillamine (Cuprimine®, Depen®): an oral chelating agent used for copper poisoning or Wilson’s disease. D -青霉胺（ cuprimine ® ，依赖® ） ：口头螯合剂用于铜中毒或威尔森氏症。 May be used in lead poisoning but not as effective as DMSA.可用于在铅中毒，但没有一样有效dmsa 。

    Deferoxamine mesylate (desferrioxamine, Desferal®): used for acute or chronic iron toxicity due to transfusion dependent anemia or aluminum toxicity in patients with chronic renal failure undergoing dialysis. deferoxamine甲磺酸（ desferrioxamine ， desferal ® ） ：用于急性或慢性毒性铁因输血依赖性贫血或铝毒的慢性肾功能衰竭患者进行血液透析。 Intravenous (IV) preferred route of administration.静脉注射（四）推荐给药途径。 Additionally, may be given subcutaneously (SQ) or intramuscularly (IM).此外，可给予皮下注射（平方）或肌注（ IM ）的。

    Deferasirox (ExJade®): an oral chelating agent used for the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older. deferasirox （ exjade ® ） ：口头螯合剂用于治疗慢性铁负荷过重，由于输血（输血血）患者的2岁和老年人。

    Dimercaprol (BAL): lead toxicity in conjunction with calcium EDTA. dimercaprol （平衡） ：铅毒性作用的结合钙的EDTA 。 Also used for arsenic, gold, and mercury toxicity.也可用于砷，金，汞的毒性。 Administered intramuscularly (IM).管理肌注（ IM ）的。

Different chelation agents are specific to certain kinds of poisonings.不同的螯合代理商所特有的某些种中毒。 For example, edetate sodium (EDTA) treatment is specific for lead poisoning and extreme hypercalcemia.举例来说， edetate钠（ EDTA ）的治疗方法是具体为铅中毒和极端高血钙症。 It has also been investigated for its effect on atherosclerosis due to suggestions of an antioxidant effect or the ability to remove calcium from arterial plaques.它也被调查及其对动脉粥样硬化，由于建议一抗氧化作用或能力，以消除钙从动脉斑块。